We’ve written here before about the bacteria that causes cavities, S. Mutans. Well new research has shown that there may be hope for a vaccine to destroy S.Mutans, effectively destroyingcavities! This informatiocomes from a report on a preclinical investigation, “Flagellin Enhances Saliva IgA Response and Protection of Anti-caries DNA Vaccine.”
The lead author of the study, Wei Shi of the Wuhan Institute of Virology in the Chinese Academy of Sciences, have notied that there is some promise for anti-cavity DNA vaccines.Shi and his team of researchers found a strain of protein that produced more likelihood that the S. Mutans bacteria would be inhibited from colonizing on tooth surfaces. The protein strain even showed a negative relationship with the likelihood of rodents’ teeth contracting cavities.
Daniel Smith of the Forsyth Institute published a response to Shi’s research which was titled “Prospects in Caries Vaccine Development.” In this response, Smith claims that thus far scientists have noticed much success in DNA vaccines for cavities when used with animals. He expects that a cavity vaccine that is based on targeting the key parts of the S. Mutans bacteria’s colonization is very likely going to be created.
The study was published in the International and American Associations for Dental Research’s official journal, the Journal of Dental Research. The Journal of Dental Research’s Editor-in-Chief, William Giannobile, said “”These papers highlight the exciting potential of using vaccines to protect against dental caries. This research is promising and provides optimism to help promote public health of caries-susceptible individuals.”
If this research becomes a reality and we are able to have a vaccine for cavities it will be a great step in the right direction for the field of dentistry. Hopeful we will be able to see the development of this vaccine in our own lifetime! In the meantime, we still need to tend to our cavities in the same way we always have by brushing and flossing aon a regular basis and maintaining excellent oral health. If you are concerned about cavities and would like to make an appointment, please visit our contact us page, or call 704-759-0908.